Cancer Care Issues - Advice From Dr. Cary Presant
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April 10, 2014

Sleep Patterns and Cancer: New Evidence

Sleep disorders are common in both men and women. The body needs adequate sleep. Recent evidence shows the value of sleep to the body is to clean out waste molecules in the brain, allowing us to function better. This observation was even listed in Science as one of the most important scientific observations of 2013.

I found recent basic science and referenced clinical studies very important. Hakim and coworkers (Cancer Research 2014, volume 74, page 1329) studied mice which had experimental tumors TC-1 or 3LLC. If the mice were subjected to sleep disruption (using a mechanical sweeper during daylight hours to fragment the sleep patterns of the mice), the cancers grew faster and became larger. Also, these tumors in sleep deprived mice were ...

Posted By: Cary Presant  

April 1, 2014

Screening Mammography Controversies in Oncology Practices

Recently there has been much ado about mammography. A Canadian study in 89,835 women, by A Miler and colleagues, Brit Med Journal 2014; 348, g366, showed no increased survival rate by screening mammography between ages 40 and 59. This has led to editorials and articles urging women at low risk not to have screening mammograms, especially between the ages of 40 and 49, which is...

Posted By: Cary Presant  

March 23, 2014

Social medial in oncology practices have you been affected yet?

Social media is an opportunity for people to interact more broadly through the internet.  Until recently, this has not impacted oncology in any meaningful way. 

However, a recent article by H. West in The Oncologist 2013; 18:780 reviewed the current status of social media.

Posted By: Cary Presant  

March 3, 2014

Oral Contraceptives May Reduce the Risk of Colorectal and Endometrial Cancers

We often see patients who are at high risk of cancer, either because they are relatives of our patients who have had cancer, or because they have had one cancer and are at risk of having other cancers.  An interesting paper has recently been published which relates to our attempts to initiate primary prevention in patients, and to d...

Posted By: Cary Presant  

February 7, 2014

Do your breast cancer patients actually complete their treatment?

A recent study in Breast Cancer Research and Treatment 2013; 138:931 by C. Friese and co-authors has identified problems in compliance with prescribed endocrine therapy in breast cancer patients after primary surgery.  They found that in 743 women eligible for endocrine therapy in whom it was recommended, 11% of the studied patients...

Posted By: Cary Presant  

February 3, 2014

Breast Cancer: To Neoadjuvant or Adjuvant, that is the Question

Neoadjuvant chemotherapy has never shown a significant impact on ovverall survival in breast cancer, so we have always wondered whether to give neoadjuvant therapy just to allow breast conservation, or to do adjuvant therapy postoperatively.

Now a new study, by von Minckwitz et al J Clin Oncol 2013; 31: 3623 has given hope that survival can be improved, and has shown statistically signi...

Posted By: Cary Presant  

January 11, 2014

At last, evidence-based adjuvant chemotherapy for patients with resected pancreatic cancer.

Chemotherapy in the past had not been recommended as evidence-based therapy for patients who had resected pancreatic cancer.  The recently published CONKO-001 study has given us evidence we have been seeking to justify use of gemcitabine in such patients.  This study (H. Oettle and co-aut...

Posted By: Cary Presant  

December 24, 2013

Proper Frequency of Screening Colonoscopy in Our Patients: American or British?

How often do we recommend repeat colonoscopy in our patients at risk of colon polyps or cancer? Do we just leave this to gastroenterologists and primary physicians, or do we make stronger recommendations to pour patents and our medical colleagues (e.g. at tumor boards)?

Posted By: Cary Presant  

December 6, 2013

Should You Help Your Colon Cancer Patients to Stop Smoking

We all that know that smoking is bad for one’s health.  Primary care physicians are most intimately involved in smoking cessation advice for patients. 

A recent study, however, indicates a new adverse impact of smoking on our patients.  A. Phipps ...

Posted By: Cary Presant  

November 30, 2013

Herbs How Should We Advise our Patients?

Here in Los Angeles, I am constantly asked about addition of herbs and vitamins to anti-cancer treatment regimens.  We are expected to answer these questions just as well as inquiries about diet and exercise. 

Fortunately, there is a new tool that can help u...

Posted By: Cary Presant  

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About This Blog

Dr. Cary Presant describes research results, observations on oncology issues, and discussions on current cancer care topics that can help improve your quality oncology care and your oncology practice.

Disclosure: Cary A. Presant, MD, has disclosed the following relevant financial relationships:
Served as a director, officer, partner, employee, advisor, consultant or trustee for: Diatech Oncology; Digital Medical Network
Received research grant from: Diatech Oncology
Have a 5% or greater equity interest in: Diatech Oncology; Digital Medical Network
Received income in an amount equal to or greater than $250 from: Diatech Oncology
Served on the Board of Directors for: Medical Oncology Association of South California; Cancer Schmancer

  • Cary Presant

    Cary A. Presant, MD, FACP, a hematologist and medical oncologist, is a staff physician at Wilshire Oncology Medical Group. He has been director of cancer programs at Washington University School of Medicine, the Jewish Hospital of St. Louis, and the City of Hope National Medical Center in Los Angeles, California. He is currently Professor of Clinical Medicine at the University of Southern California School of Medicine. Dr. Presant's current research includes pharmacologic improvement of chemotherapy effectiveness by magnetic resonance spectroscopy, as well as the development of a new chemotherapy sensitivity test, based on apoptosis, for all types of cancer. He is the author of over 400 scientific articles in cancer treatment, cancer detection, chemotherapy, experimental tumor biology and pharmacology, liposomes for cancer diagnosis and therapy, magnetic resonance spectroscopy, measurement of quality of life in cancer patients, and quality care in oncology. As an author, Dr. Presant has written Navigating American Medicine, soon to be published, and is the physician columnist for the national patient Website Dr. Presant is past president of the California Division of the American Cancer Society, Chairman of the Board of Directors of the Medical Oncology Association of Southern California (MOASC), past Director of the American Society of Clinical Oncology (ASCO), and past president of the Association of Community Cancer Centers (ACCC).

The content of this blog does not necessarily reflect the viewpoints of Medscape.
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